Outcome Of Children With Acute Post Streptococcal Glomerulonephritis in Tikur Anbessa Specialized Teaching Hospital Addis Ababa, Ethiopia

Abstract

Back Ground: post streptococcal glomerulonephritis is one of the commonest causes of
glomerular disease in developing countries. It is also one of the commonest causes of morbidity
and in few cases mortality if proper identification and supportive treatment is not delivered.
Objective: the objective of this study is to look into the outcome and identify the predictors of
outcomes of patients with post streptococcal glomerulonephritis in a tertiary care hospital.
Materials and methods: Retrospective analysis of admissions of post streptococcal
glomerulonephritis was conducted at Tikur Anbessa Specialized Teaching Hospital in Addis
Ababa over eight year’s period from 2003 to 2010. Data was collected from patient records.
The record of each patient was examined for the following information: age, sex, and address
sociodemographic characteristics, predictors of outcome and complications of APSGN.
Results: there were 68 children with APSGN enrolled during the study period. 40 (58.8%)
were males and 28 (41.2%) were females. The common age group of presentation was between 6
and 10years (30/68, 44.1%) followed by 3 and 5years (21/68, 30.9%). The age range was
between 2.5-14years with a mean age of 7.5years.Two patients had unusual age of presentation
one at 2years and 6 months and the other at 2yrs and 11months. 44 (64.7%) had sore throat or
skin infection before presentation while 24(35.3%) did not give any history of infection before
presentation.
Fifty two (76.5%) patients were from Addis Ababa and 14 patients presented from Oromia
region around Addis Ababa while 2 patients came from remote areas
Thirty two (47.1%) patients had follow up at the renal clinic for a duration,of 6 months - 1
year while the remaining were followed for less than 6 months and were released from follow up
when they were stabilized.
Conclusion: There was no significant association between age, sex, renal dysfunction and
severity of hypertension to the outcome of patients and .there was no complication observed
during the follow up period.